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Pharmacophore modeling and 3D-QSAR studies on substituted benzothiazole / benzimidazole analogues as DHFR inhibitors with antimycobacterial activity

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Academic year: 2017

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TABLE 2:Activity Table:  S.NO  COMPOUND  ID CODE   R  MIC  µg/ml   -log MIC  GFA  Predicted
FIGURE 1. Pharmacophore models for DHFR inhibitors.   HypoGen features with its distance constraints
FIGURE 4: Superimposition of aligned fit molecules
FIGURE 7:GFA GRAPH
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