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Antimicrobial activity of human prion protein is mediated by its N-terminal region.

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Academic year: 2017

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Figure 1. Antimicrobial effects of recPrP and variants. (A) In viable count assays, Escherichia coli and Candida parapsilosis were subjected to increasing doses of PrP in 10 mM Tris pH 7.4 (left panel) or 10 mM MES pH 5.5 (both containing 5 mM glucose) and
Figure 3. Activities of peptide sequences of PrP. (A) Antimicrobial activity of selected peptides (at 100 mM in RDA) against the indicated microbes
Figure S1 Antimicrobial effects of histidine-rich peptides at low pH. In viable count assays, Candida parapsilosis were subjected to increasing doses of the peptides AHH24; AHHAHAAHH  AH-AAHHAHAAHHAHA (left panel) and GHH20;  GHHPHGH-HPHGHHPHGHHPH (right p

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