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Perilipin1 deficiency in whole body or bone marrow-derived cells attenuates lesions in atherosclerosis-prone mice.

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Academic year: 2017

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Fig 1. Plin1 expresses in atherosclerotic lesions. (A) Immunoblotting analysis of Plin1 expression in perivascular adipose tissue and in peritoneal macrophages isolated from Plin1-/- and wild-type mice
Fig 2. Lipid content is decreased in peritoneal macrophages and foam cells derived from Plin1-/- mice
Table 1. Plasma cholesterol, triglyceride and body weight in ApoE-/- and Plin1-/-ApoE-/-mice after 12 weeks on western diet.
Fig 3. Ablation of Plin1 restricts As in female ApoE-/- mice. (A and B) The mean lesion area (±SEM) in the aortic roots of male (A) and female (B) ApoE-/- ApoE-/-and  mice, *** p < 0.001
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