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DNA methylation dynamics in human induced pluripotent stem cells over time.

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Academic year: 2017

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Figure 1. Pluripotent stem cells are significantly more hyper-methylated than their parent cells
Figure 2. Defining stem cell-specific DMRs as novel epigenetic iPS markers. (A) Venn-like diagram showing overlapping CpG sites among ESCs, iPSCs and their parent cells
Table 1. List of the top 20 out of 82 transcription factor genes with hypo-methylated stem cell-required DMRs exhibiting ‘‘high’’
Figure 6. Hyper-methylation in the ES-iPS-DMRs and ES-parent-DMRs. ES-iPS-DMRs that disappeared in UtE-iPS-11 and Edom-iPS-2 at the latest passage (upper) were analyzed and the methylation score of each ES-iPS-DMR was plotted on bar graph (middle)

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