Quercetin Protects against Okadaic Acid-Induced Injury via MAPK and PI3K/Akt/GSK3β Signaling Pathways in HT22 Hippocampal Neurons.

Another investigation also demonstrated that inhibition of PI3K/Akt signaling by Cbl (Cbl-b and c-Cbl) may be involved in both ATO-induced apoptosis of NB4 cells and ATO-induced

In the present study, we demonstrated that Que postconditioning attenuates myocardial I/R injury in rats via activating the PI3K/Akt pathway and modulating Bcl-2 and Bax

To explore the mechanisms of quercetin in pulmonary angiogenesis, mRNA and protein levels of VEGF-A were assessed, and found to be signi fi cantly decreased after quercetin

antagonist, protects mice against acute pancreatitis and associated lung injury. Expression of the chemokines MCP-1/JE and

Seventeen compounds, mainly methyl ethers of quercetin (isorhamnetin, rhamnazin), kaempferol (kaempferide, rhamnocitrin), and ellagic acid as well as quercetin, quercetin

Pancreatic GSSG, GSH levels and GSH/GSSG ratios in control rats and rats with cerulein induced pancreatitis, untreated or treated with quercetin.. Oxidative stress and cytokines

We propose a model in which the JNK and AKT/ GSK3 b pathways are activated independently and converge to regulate transcription factors including FoxO3a that mediate

The in vitro results showed that nicotine up-regulated the expression of α 5-nAChR protein and inhibited cis- platin-induced apoptosis by regulating α 5-nAChR/AKT signaling pathway