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Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development.

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Academic year: 2017

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Figure 1. Generation of Cul4b flox mice. (A) Strategy for generation of Cul4b floxed targeting vector
Figure 2. Morphology and histology of Cul4b null embryos. (A) Uterus excised from pregnant female at 12.5 dpc
Figure 5. Morphology and histology of placentas of wild-type, Cul4b heterozygous and absorbed embryos at 14.5 dpc

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