Hemizygous Le-Cre transgenic mice have severe eye abnormalities on some genetic backgrounds in the absence of LoxP sites.

Histological analysis using haematoxylin and eosin staining of sections of cardiac muscle from 2–4 month old transgenic mice from each the four lines showed no differences compared

To analyse whether split-Cre complementation induces recombination activity in vivo , we generated transgenic mice expressing NCre and CCre under the control of the mouse

(J) The histogram describes the levels of pERK (expressed in arbitrary units) in projection neurons of the wild-type mice, R6/2 HD mice treated with saline and R6/2 HD mice treated

Here, we report for the first time the generation of Fgf5-P2A-Venus BAC transgenic (Tg) mice and show that the BAC Tg can recapitulate endogenous Fgf5 expression in epiblast

We do not know at which stage GFAP-Cre mediated transgene activation is accomplished in our transgenic model although enhanced expression of Bmi1 in Gcre;Bmi1 LSL mice in

We addressed the potential role of miRs in the pathogenesis of DMD, consi- dering that, in muscle tissue obtained from mdx and transgenic mice ( a -and b -sarcoglycan knockout

Oral administration of ground cinnamon suppresses clinical symptoms of EAE in female PLP-TCR transgenic (Tg) mice, adoptive transfer model in female SJL/J mice and chronic model in

Based on these lines of evidence, together with previous studies demonstrating that Cre-mediated recombination in cells with inverted loxP sites in the genome can cause chromosome