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Blocking TGF-β Signaling Pathway Preserves Mitochondrial Proteostasis and Reduces Early Activation of PDGFRβ+ Pericytes in Aristolochic Acid Induced Acute Kidney Injury in Wistar Male Rats.

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Academic year: 2017

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Fig 1. Representative histological findings in a human case of end-stage aristolochic acid nephropathy (AAN)
Fig 2. Schema showing the proposed hypothesis of tubular and vascular injury and perivascular cells involvement in the pathogenesis of aristolochic acid (AA)-related kidney fibrosis
Fig 3. Anti-transforming growth factor beta (TGFβ) Ab suppressed p-Smad2/3 signaling in the kidney induced by aristolochic acid (AA) and attenuated acute kidney injury
Fig 5. Anti-transforming growth factor beta (TGFβ) Ab attenuated aristolochic acid (AA)-induced ultrastructural alterations within the tubulointerstitial compartment
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