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Activation of adenosine A2A receptors induces TrkB translocation and increases BDNF-mediated phospho-TrkB localization in lipid rafts : implications for neuromodulation

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Academic year: 2021

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Figure 1. Activation of adenosine receptors enhances the levels of TrkB full length and potentiates BDNF-induced pTrkB localization in lipid rafts
Figure 4. A 2A receptors are not required for maximal BDNF-induced TrkB translocation to lipid rafts
Figure 6. SignalingpathwaysinvolvedinCGS21680-inducedTrkBtranslocationtolipidrafts.Culturedcorticalneuronswereincubated with/without20n M CGS21680for30mininthepresenceoftheadenylatecyclaseactivatorforskolin(5 ␮ M ),thePKAinhibitorH-89(1 ␮ M ), the cAMP ant
Figure 7. Effects of cholesterol depletion and loading on the partition of TrkB receptors to lipid rafts and on adenosine A 2A receptor binding properties
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