Thalidomide protects mice against LPS-induced shock

Thus, WT, TLR4KO, MyD88KO and TRIFmut mice were treated with 10 m g of S-LPS or R-LPS and the influx of polymorphonuclear cells (PMNs) into BALF, as well as the BALF concentrations

(J) The histogram describes the levels of pERK (expressed in arbitrary units) in projection neurons of the wild-type mice, R6/2 HD mice treated with saline and R6/2 HD mice treated

8-oxoG, PARP-1 and MUTYH are increased in cerebellum of FA mice treated with introcerebraventricular injection of LPS compared with wild-type mice received the same treatment.. (A)

Since the LPS-induced loss of dopaminergic neurons was enhanced in DJ-1 KO mice, we inves- tigated whether the LPS-induced expression of IFN- γ and I-TAC in the substantia nigra

Mice missing functional caspase 1/11 or caspase 11 had equivalent airway inflammation after LPS challenge compared to the wild type control mice suggesting these proteins are

Figure 7. In vivo IL-12 neutralization during vaccination generates defective effector memory but not central memory CTLs. All mice were treated with Abs against IL-12p40 or an

Once again, the results presented above were in line with the significant body weight gain observed in mice treated with the nitrotriazoles (compounds 3 and 5) but not mice treated

Surprisingly, the restrained pathogenic response was not related to IL-10 production, as evidenced by lower levels of both mRNA, protein expression in lesions from co-infected mice