PIPKIγ regulates focal adhesion dynamics and colon cancer cell invasion.

Together, these results revealed that CD147 is involved in vinculin-mediated focal adhesion formation, which subsequently promotes cytoskeleton reorganization to facilitate invasion

Angiotensin II stimulates tyrosine phosphorylation of the focal adhesion protein paxillin in aortic smooth muscle cells. Role of focal adhesion kinase in

The FERM domain plays an essential autoinhibitory role in the regulation of the cata- lytic activity of FAK [ 8 ], in which the F2 subdomain contacts the C-lobe of the kinase

Using a murine Burkitt´s lymphoma model over-expressing human c-MYC [β0], we show here that immunization of mice with human c-MYC protein and c-MYC derived

Cell adhesion, invasion and migration assay demon- strated that overexpression of the second FAS1domain promoted the amounts of cell adhesion, invasion and migration to

Reduced cell spreading and focal adhesion formation in Fmn1-IV 2/2 MEFs further demonstrates the role of Formin family members in cellular processes that involve regulation of

Hypersensitive C-reaction protein, homocysteine, intercellular adhesion molecule 1, vascular cell adhesion molecule 1, matrix metalloproteinase-9, tissue inhibitor

CONCLUSIONS: Our data suggest that despite the relevance of focal adhesion kinase and src homology 2 domain- containing protein-tyrosine phosphatase 2 in hematopoietic disorders,