Determining host metabolic limitations on viral replication via integrated modeling and experimental perturbation.

Viral hepatitis A, B, C, D and E – systemic hepatotropic viral infections – present as acute hepatitis that, depending on the etiological agent, viral load and host conditions,

With this viral dynamics food web module (model 2), we then look at how in-host life history trade-offs mediate competition and the disease burden between virulent and

We used a mouse model of inflammatory colitis, caused by the attaching and effacing pathogen Citrobacter rodentium [14,15], to investigate dynamic changes in microbial

Therefore, to clarify the relationship between viral replication and host cytokine response against infection of the HPAIVs at an individual level, we assessed the correlation

To elucidate the in vivo involvement of PSGL-1-dependent replication and pathogenesis, and the role of amino acid polymorphism at VP1-145, we investigated viral replication,

As multiple Mimivirus capsid progeny are generated, large host cisternae that act as viral lipid reservoir are excluded from the membrane assembly zone, thus highlighting the need

Changes in the viral protein length relative to the host related proteins in the same protein Pfam family could be due to a shortening of IDOL (inter- domain linkers) and the

Human cytomegalovirus (HCMV) and rhesus cytomegalovirus (RhCMV) express a viral interleukin-10 (cmvIL-10 and rhcmvIL-10, respectively) with comparable immune modulating properties