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Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions.

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Academic year: 2017

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Figure 1. DNA binding cooperativity extends the p53 cistrome to low affinity binding sites
Figure 2 Cooperativity reduces the sequence specificity of p53 DNA binding. (A) Classification of genomic regions
Figure 6. Role of DNA binding cooperativity for the survival of breast cancer patients
Figure 7. p53-dependent gene repression requires high DNA binding cooperativity. (A) The percentage of differentially regulated genes with or without a p53 binding site in our ChIP-seq dataset

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