A Susceptible Mouse Model for Zika Virus Infection.

Infection of IFN- c R- and TNFRp55-deficient mice revealed a higher number of blue cells in the spleen compared to infected WT mice indicating that either more host cells

cells expressing IFN c and Pfn in the spleen, peripheral blood and cardiac tissue during the acute and chronic infection of C57BL/6 mice.. In the acute infection (45 dpi), there

Reduced trabecular thickness and BV/TV also were seen in male Akt2-deficient mice and their wild-type littermates compared with male wild-type mice from comparable Akt1-

Finally, treatment of wild type mice with dexamethasone resulted in a significant increase in endogenous brain A b levels, which was prevented in mice genetically lacking

In the absence of type I and II IFN receptors or the transcription factor STAT1, suckling mice are deficient in IFN signaling and become much more susceptible to heterologous, but

( A,B ) Blood samples from EAE-affected wild-type (WT, n = 6) and EphA4 knockout (KO, n = 9) mice were taken at 20 days post-immunisation and pNF-H levels were measured as an

Using mice deficient in interferon α / β and Ɣ receptors (AG129 mice), we report that these animals were highly susceptible to ZIKV infection and disease, succumbing within seven

Effects of alpha1 antitrypsin (A1AT) on SPLUNC1 protein levels in bronchoalveolar lavage (BAL) fluid of wild-type and ENaC transgenic (Tg) mice after 3 days of infection.. Mice