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Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN.

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Academic year: 2017

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Figure 5. PTEN was the downstream target of miR-21 during reversing EMT and CSC phenotype
Figure 6. MiR-21 regulated EMT and CSC phenotype through mediating AKT and ERK1/2 activation
Figure 7. Schematic diagram of the proposed model: possible mechanism of miR-21 regulates EMT and CSC phenotype.

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