• Nenhum resultado encontrado

A Role for MicroRNA-155 Expression in Microenvironment Associated to HPV-Induced Carcinogenesis in K14-HPV16 Transgenic Mice

N/A
N/A
Protected

Academic year: 2021

Share "A Role for MicroRNA-155 Expression in Microenvironment Associated to HPV-Induced Carcinogenesis in K14-HPV16 Transgenic Mice"

Copied!
15
0
0

Texto

Loading

Imagem

Table 1. Primer sequences.
Table 2. Association between the characteristic phenotype of HPV – associated lesions and genotype of HPV E6/E2 DNA of mice.
Figure 1. Mice genotyping. The presence of integrated HPV was assessed by amplification of HPV-E2 (b) and HPV-E6 (c) genes by polymerase chain reaction methodology (PCR) in-house
Figure 2. Wild-type (-/-) and K14-HPV16 transgenic (+/-) mice. Transgenic mice show a hunched position, partial thoracic and cephalic alopecia, together with extensive hyperkeratosis and auricular erythema.
+5

Referências

Documentos relacionados

Expression of hMTH1 in the transgenic mice conferred a significant protection against paraquat-induced oxidative DNA damage and DNA 8-oxodG levels in these organs were between 4-

The results show that a higher miR-155 and miR-132 expression in PBMC was associated to MS patients compared to healthy donors, but the results also showed two different patterns

To compare the normalized data from dysplasia, normal lung tissue from transgenic mouse, tumor cells and non-transgenic of different mice, we used the Significance Analysis

To assess the effect of loss of functional PER3 on circadian organization, we analyzed the phases of PER2::LUC expression in tissues explanted from wild-type and Per3 2 / 2 mice

Expression of these vascular miRNAs miR-125b, miR-145, and miR-155 was decreased in the thoracic aorta in CKD rats compared to normal rats, with concordant changes in target genes

Unexpectedly, Western-blot analyses showed that HSF1 levels are reduced in both the striatum and in the cerebellum of HD knock-in mice compared to wild-type mice (Figure 6 A). In

Inhibition of HO-1 by ZnPP, however, restored brain cellular infiltrates in miR-155 -/- mice to numbers comparable to those observed in wild type counterparts, again supporting a

In contrast, transgenic mdx mice with skeletal muscle expression of Dp260, the retinal isoform of dystrophin, showed significant nNOS expression in muscle membrane fractions yet