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Characterization of T follicular helper (Tfh) cells and B cell isotype switching induced by type 1 and type 2 adjuvants

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Academic year: 2021

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Figure 1.1- Compartments and dynamic of the GC. Centroblasts undergo somatic  hypermutation and clonal expansion into  the DZ
Figure 1.2- Major pathways of  naïve CD4+ T cell differentiation into effector  cells
Figure 1.3- Cellular and  molecular interactions between DCs, Tfh and B cells  in  GC
Figure 1.4- Canonical model of Tfh cell differentiation. Multiple signals and steps  for  the  generation  of  Tfh  cells
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