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Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT.

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Academic year: 2017

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Figure 1. Intensive crosstalk between CRC and MRC-5 cells in the tumor microenvironment
Figure 3. Targeting human colon cancer stem cells (CD133 positive cells) with curcumin and/or 5-FU in high density tumor microenvironment co-culture
Figure 4. Curcumin sensitizes colon cancer stem cells to 5-FU in the high density tumor microenvironment co-culture
Figure 8. High density tumor microenvironment co-cultures induce EMT with loss of epithelial markers and increase of mesenchymal markers
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