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Alendronate induces gastric damage by reducing nitric oxide synthase expression and NOcGMPKATP signaling pathway

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Academic year: 2018

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Fig. 1. Effect of (A) sodium nitroprusside (SNP) and (B) L -arginine ( L -Arg) pretreatment on alendronate-induced gastric damage
Fig. 2. Histopathological changes in the gastric mucosa (40 magnification). (A) Control (saline) group showing gastric mucosal integrity
Fig. 4. Role of soluble guanylate cyclase (sGC) and ATP-sensitive K + channels (K ATP ) in the gastroprotective effect of sodium nitroprusside (SNP) and L -arginine ( L -Arg) in a rat model of alendronate-induced gastric damage
Fig. 5. Role of nitric oxide synthase (NOS) in alendronate-induced gastric damage.
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