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Establishing a Diphtheria Toxin-sensitive system for cell ablation within the embryonic small intestine in mouse

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Academic year: 2021

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Figure 1. 1. Structure of the adult small intestine in mammals. The tubular small intestine is formed by 3 main  layers of different tissues – the mucosa, the submucosa and the muscularis mucosa
Figure 1. 4. Schematic representation of embryonic intestinal development in mouse. (A) From E8.0 to E9.5,  the primitive gut tube is formed
Figure 1. 8. Signalling pathways involved in the maintenance of intestinal homeostasis and their gradients  of expression along the crypt-villi axis
Figure  1.  9.  Schematic  representation  of the  canonical Wnt/β-catenin  pathway.  In  the  absence  of  the  Wnt  ligands Fzd and LRP5/6, β-catenin is degraded and the Wnt target genes are not expressed (a)
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