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Gold nanoparticles for nanotheranostics in leukemia – Addressing Chronic Myeloid Leukemia

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Table 1.1 Common genetic abnormalities associated to leukemia. 11,20 Subtype  Frequent genetic biomarkers
Figure 1.1 Structure of BCR-ABL1 isoforms. P210 BCR-ABL1  isoforms represent 95 % of Ph+ CML cases  and  may  derive  from  two  transcript  types  (e14a2  or  e13a2)  due  to  alternative  splicing  events
Table 1.2 Expected levels of CML patients response after TKI therapy initiation (ELN guidelines)
Table 1.3 TKIs in CML management. Adapted from Leach, 2016. 63
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