Advances and challenges in therapeutic monoclonal antibodies drug development

The other mAbs that failed to react in Western blot (1D12, 22C1, 4B2) reacted with antigens of the parental virus (Los Angeles) but failed to react with cells infected with

Surface antigens analysis of group B Neisseria meningitidis Outer membrane by monoclonal Antibodies: Identification of bactericidal antibodies to class 5 protein. Human

BSA: Bovine serum albumin; iELISA: Indirect ELISA; KLH: Keyhole limpet hemocyanin; mAb: Monoclonal antibody; PLA 2 : Phospholipase A 2 ; PLIγ:.. Gamma type phospholipase A 2

In the present study, we compared sensitivity and cost/ beneit between the novel rabbit monoclonal antibodies and two most used mouse monoclonal antibodies, developing the antigen

CH2 and CH3 constitute the crystallizable fragment (Fc re- gion), responsible for antibody serum half-life via the neonatal Fc recep- tor (FcRn), and effector functions via Fc

Drug production in rural areas requires a classical tech- nology entirely independent of rDNA and monoclonal antibodies but of great economic and social importance to the

Several proteins have been studied in relation to the development and progression of colorectal cancer, including tumor protein p53 (p53) and antigen identiied by monoclonal

The samples of the bovine serum, unpurified IgG and purified IgG (by chromatography) were submitted to electrophoresis SDS-PAGE and Western Blot. The samples were