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Abdominal Aortic Aneurysm: a review on the role of oral antidiabetic drugs.

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Academic year: 2021

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Table I –Characteristics of the studies included for the association of OAD and AAA formation/ AAA growth Controled for ---   MORE THAN ONE ANTIDIABETIC DRUG Follow-upduration,  socioeconomicstatus,  age, sex, adapted Diabetes complications SeverityIndex s
Table I (continued) –Characteristics of the studies included for the association of OAD and AAA formation/ AAA growth Controled for MORE THAN ONE ANTIDIABETIC DRUG Age, ethnicity, smokingstatus,  comorbidities,and medication use at time  of AAA diagnosis *
Figure 1. - Flowchart representative of the study selection procedure.
Figure 2. - Hypothesized mechanisms underlying the protection conferred by OAD. AMPK  activation is thought to be the major mechanism through which metformin has a vascular  protective effect

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