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The adult livers of immunodeficient mice support human hematopoiesis: evidence for a hepatic mast cell population that develops early in human ontogeny.

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Academic year: 2017

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Figure 1. Engraftment of the murine liver with human blood cells. (A) A NOD-SCID mouse transplanted with human CD34 ++ CD45 + hFL cells was analyzed 71 days after transplant revealing high level engraftment of human CD45 + CD59 + cells in the BM, spleen an
Figure 2. Mature human blood cells in the murine liver. (A) Significantly more light-density liver cells were recovered from 3 mice transplanted with CD34 ++ CD38 2 hFL cells than from untransplanted NSG mice
Figure 4. Human hematopoiesis in the livers of mice transplanted with fetal cells. (A) Hematopoietic precursors are present in the liver of a mouse analyzed 130 days after being transplanted with 16 10 6 hFL cells
Figure S1 Human engraftment in the livers of mice with indication of graft versus host disease

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