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Julia Penna Coutinho 1,2 , Anna Caroline Campos Aguiar

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Academic year: 2019

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Fig. 1: Aspidosperma nitidum, a medicinal plant named carapanaúba,  from which the wood bark material was collected and used to prepare  extracts  and  fractions  that  displayed  high  antimalarial  activity  and  low toxicity, in vitro and in vivo.
Fig.  3:  extracted  chromatograms  comparison  at  254  nm  of  MeOH  crude  extract  (A)  and  fractions,  precipitate  (B),  FO  III  (C)  and  FO  IV (D).
Fig.  4:  mean  parasitaemia  by  Plasmodium  berghei  in  mice  infected  with  chloroquine-resistant  parasites  following  treatment  for  three  consecutive days with the test compounds, evaluated on the fifth (A)  and seventh (B) days after inoculatio

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