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Development and optimization of production and purification of the human protein BMP-2 in Escherichia coli for biomedical applications

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Academic year: 2020

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Figure 2: Gene transcription by BMP-Smad activation. Adapted from [ 4 ]
Table 1: Selected works reporting the production of rhBMP-2 in different expression systems
Table 2: Studies of the production and purification of rhBMP-2 in E.coli.
Figure 3: a) Model structure of FH8 in the closed conformation (yellow). After calcium ligation occur a change to open conformation (green) and on the right is possible to see in detail the calcium binding loops, where calcium ions are r
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