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Differential expression of Wnts after spinal cord contusion injury in adult rats.

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Academic year: 2017

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Figure 1. Wnt ligands expression in the spinal cord of adult rats following SCI. All Wnt ligands except for Wnt3, 3a, 8a and 8b were constitutively expressed in the non-injured adult spinal cord
Figure 2. Short term up-regulation of Wnt inhibitors expression after SCI. Expression of the Wnt inhibitor genes Dkk-1/4, sFRP (sFRP-1/5) and Wif1 was quantified by qRT-PCR as described in Figure1
Figure 3. SCI alters the mRNA expression of canonical Wnt signalling components. Expression of the canonical co-receptor LRP5/6, the downstream intracellular inhibitory transducer GSK3-ß and the ß-catenin transcription factor were quantified by qRT-PCR as
Figure 5. Temporal expression of Wnt mRNAs, and a schematic representation of Wnt signalling elements

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