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Identification of MAMDC1 as a candidate susceptibility gene for systemic lupus erythematosus (SLE).

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Figure 1. Identification of MAMDC1 as the SLE susceptibility locus in the 14q21-q23 linkage region
Figure 2. Individual and pooled odds ratios for rs961616 and rs2297926. The individual and pooled contribution of each sample population for rs961616 (A) and rs2297926 (B), shown as ORs.
Figure 4. Comparison of homologs of the human MAMDC1 protein. Alignment of MAMDC1 full-length polypeptide with other proteins containing identical structural domains (reported on the left: MAM, meprin/A5-protein/PTPmu; FNIII, fibronectin, type III-like fol
Figure 5. Analysis of MAMDC1 mRNA expression. Northern blot analysis of MAMDC1 mRNA expression in different human tissues, showing several expressed splice variants

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