PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells.

In the present study, the slightly differentiated adenocarcinoma group had the highest Rac1 expression level and in QBC939 cells, the RNAi group showed more apoptosis than

Um novo modelo sobre a protecção de sistemas de energia eólica foi desenvolvido e sujeito a simulação com o programa de computador EMTP-RV.. Os resultados da simulação com o

The increased levels of caspase-3 activation suggest that silver nanoparticles induced apoptosis in MCF 7 breast cancer cells in a caspase-3-dependent manner..

In the UUO group, HIF-1 a expression was increased in tubular epithelial cells and fibrotic areas at day 3 compared with the control and hAFSC groups; this increase in HIF-1

As shown in Figure 1A, HIF-1a protein levels increased in these cells when compared to those cultured at atmospheric oxygen concentrations (20%), while levels of HIF-2a did not

In this study, we determined that HIF-1a expression in lung tissues increased in LPS-induced ALI mice, whereas TNF-a secretion in lung tissues and serum increased

pylori for 30 min or 1h or left uninfected and Rac1 activity was measured by detecting levels of GTP- bound Rac1 in AGS (A) and NCI-N87 (B) cells that were transfected with

Based on these data, we suggest that BCAR3 controls the balance between Rac1 and RhoA signaling in invasive breast cancer cells and, through this activity, functions as a