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IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland.

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Academic year: 2017

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Figure 2. PP2Ce and IRE1 a expression in peri-partum mouse mammary gland. A. PP2Ce and B
Figure 4. Mammary gland defects in postpartum PP2Ce deficient mice. A. Representative H&E images (10X lens) of mammary tissue from wildtype (a and c) and PP2Ce -/- (KO) (b and d) at postpartum day 0 (L0) and day 2 (L2), showing reduced alveolar density
Figure 6. Stress signaling activation in postpartum PP2Ce deficient mammary gland. A. Immunoblot of phospho-JNK, phospho-p38 and Caspase 12 activation (cleaved) levels in PP2Ce +/+ and PP2Ce -/- mammary tissue at day 0 (L0) or day 2 post parturition (L2)

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