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Distinct actions of akt1 on skeletal architecture and function.

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Academic year: 2017

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Figure 1. Reduced bone strength in femurs from heterozygous and homozygous Akt1 deficient male mice
Figure 6. Reduced proliferation but normal osteogenic differentiation of bone marrow stromal cells from Akt1 deficient male mice.
Figure 8. Normal proliferation and differentiation of calvarial osteoblasts from Akt1 deficient mice
Figure 9. Reduced osteoclast formation in Akt1-deficient mice. Bone marrow macrophages were isolated from 20-week mice of the indicated genotypes, and incubated in osteoclastogenic medium for 6 days as described in ‘Materials and Methods’

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