Transcriptional Fingerprint of Hypomyelination in Zfp191null and Shiverer (Mbpshi) Mice

Consequently, we found that the HtrA1 transcripts (Figure 1C) and protein expression were also reduced in the pancreatic cancer cell lines PANC-1 and BXPC-3 compared with the

In the present study, we characterize the expression of TAM receptors in the mouse CNS and demonstrate that Gas6 promotes oligodendrogenesis directly via Tyro3 receptor,

Given that mice deficient in Apoe show vascular permeability, decreased CBF, synapse loss, and cognitive impairments [ 37 , 75 , 76 ], a decrease in Apoe expression in the aging

Given that Msx2 expression was markedly reduced in the developing skull of Foxc1 mutant mice [7], we wished to test whether loss of FOXC1 expression in human cells would reduce

In conclusion, we found that MHCI proteins are expressed in the NAc of WT mice. We also found that LTP is enhanced whereas LTD is abolished in functional MHCI-deficient mice. We

In zebrafish, we overexpressed mutant HOMER2 and ob- served inner ear defects; and in mice we documented robust expression in stereocilia of co- chlear hair cells and demonstrated

For example, in Ercc1-deficient mice hematopoiesis is impaired and bone marrow cellularity and hematopoietic progenitor cell (HPC) numbers are reduced [22]; in mice deficient in

Not surprisingly we therefore find that the lower casein protein levels in a-casein deficient mice are accompanied by a significantly lower concentration of calcium and phosphate