Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase-3 activation, decreased Bcl-2 levels, increased p53 expression and PARP cleava

The increased levels of caspase-3 activation suggest that silver nanoparticles induced apoptosis in MCF 7 breast cancer cells in a caspase-3-dependent manner..

Expression of the A88V and G11R mutants resulted in elevated levels of the cleaved forms of caspase-3, caspase-8, caspase-9, and PARP, which are all markers of apoptotic

Ca 2+ -Mg 2+ -ATPase and succinate dehydrogenase levels and myocardial Bcl-2 and Caspase-3 protein expression levels were significantly increased (P<0.05), the left

A Educação Física Escolar (EFE) tem seu papel fundamental para favorecer uma vida mais ativa na in- fância e adolescência, incentivando estilos de vida sau- dáveis na fase adulta,

With the increase of matrine concentration, the relative expression level of Bcl-2 protein in CNE-2 cells was decreased, and the expression level of Caspase-3 protein was

abieslactone inhibited the growth and proliferation of three human hepatoma cell lines (HepG2, SMMC7721, and Huh7) but had low cytotoxicity to normal hepatic cells (QSG7701). HepG2

Chlorella vulgaris at 2 mg/ml (optimal dose) induced higher expressions of P53 (a), Bax (c) (proapoptotic) and caspase-3 (d) proteins in HepG2 cells compared to the control cells

RESULTS: Prima-1 was able to reactivate p53 function in the T24 (p53 mt) bladder cancer cell line and promote apoptosis via the induction of Bax and Puma expression, activation of