• Nenhum resultado encontrado

Abieslactone induces cell cycle arrest and apoptosis in human hepatocellular carcinomas through the mitochondrial pathway and the generation of reactive oxygen species.

N/A
N/A
Protected

Academic year: 2017

Share "Abieslactone induces cell cycle arrest and apoptosis in human hepatocellular carcinomas through the mitochondrial pathway and the generation of reactive oxygen species."

Copied!
19
0
0

Texto

Loading

Imagem

Fig. 1. The chemical structure of abieslactone and its growth-inhibiting effect on HepG2, SMMC7721 and QSG7701 cells
Fig. 2. Abieslactone-induced apoptosis in HepG2 and SMMC7721 cells. (A) Apoptosis was evaluated using an annexin V-FITC apoptosis detection kit and flow cytometry
Fig. 3. Nuclear morphology of HepG2 and SMMC7721 cells treated with 5, 10, and 20 mM abieslactone or 20 mM Z-VAD-FMK for 24 h was determined by staining with Hoechst 33258.
Fig. 4. The effect of abieslactone on the cell cycle and the expression of cell cycle regulators in HepG2 and SMMC7721 cells
+5

Referências

Documentos relacionados

Tamoxifen induces suppression of cell viability and apoptosis in the human hepatoblastoma cell line HepG2 via down-regulation of telomerase activity. Jaber BM, Mukopadhyay R,

Silencing of augmenter of liver regeneration inhibited cell proliferation and triggered apoptosis in U266 human multiple myeloma

Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction

Nesta secção expomos os fundamentos da nossa tese de doutoramento: “eBook como um Dispositivo Pedagógico no Ensino e na Aprendizagem da Biologia e da Geologia: Um estudo com alunos

Experiment 2 “Effect of high water temperature 33ºC, on White Spot Syndrome Virus WSSV infection in pacific white shrimp Litopenaeus vannamei, when applied at different times 12 and

Exosomes secreted from human colorectal cancer cell lines contain mRNAs, microRNAs and natural antisense RNAs, that can transfer into the human hepatoma HepG2 and lung cancer

Oridonin has been reported to induce cell apoptosis and cell cycle arrest in many cancers, and our results revealed that oridonin inhibited cell growth, promoted cell apoptosis,