Sfrp5 modulates both Wnt and BMP signaling and regulates gastrointestinal organogenesis [corrected] in the zebrafish, Danio rerio.

The Wnt-3a protein partially protected PC12 cells, with a 6-15% increase in cell viability in the presence of toxic agents, similar to the effect measured using the MTT and

In order to identify another Wnt pathway proteins in these same samples we propose the study of two non-canonical pathway proteins (Wnt-5a, FZD5) and six canonical pathways proteins

Immunohistochemistry analysis of Panc4.21 and L3.6sl pancreatic cancer cell lines shows that inhibition of the Wnt signaling pathway using anti- b - CATENIN siRNA (100nM) results in

In conclusion, we have shown that a targeted Apc mutation encoding for intermediate levels of Wnt/ b -catenin signaling results in a highly penetrant predisposition to

In addition, gene and protein expression of b -catenin correlates positively with that of integrin b 4 and both are strongly suppressed in laminar basal epithelial cells of

Given that we observed defects in the survival of migrating cranial neural crest cells together with defects in placode development, we carefully examined the interactions between

Maternal Wnt signaling is required for Xenopus dorsoventral axis formation [31] and depletion of maternal axin1 mRNA in Xenopus results in elevated Wnt/ b -catenin activity

Because differential activation of canonical Wnt signaling in FOb and POb plays an important role in determining substantial differences in their osteogenic potential, as well as