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Low transformation growth factor-β1 production and collagen synthesis correlate with the lack of hepatic periportal fibrosis development in undernourished mice infected with Schistosoma mansoni

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Academic year: 2019

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Fig. 1: worms recovered in well-nourished (WI) and undernourished-infected mice (UI) in both acute (A) and chronic (B) phases of Schistosoma  mansoni infection
Fig.  2:  liver  histopathology.  A:  well-nourished  infected  mouse  with  Schistosoma  mansoni
Fig. 4: morphometric measurements of the mean volume (A), volume density (B) and numerical density (C) of egg granulomas in undernour- undernour-ished-infected (UI) and well-nourished (WI) mice in the acute and chronic phases of Schistosoma mansoni infecti
Fig. 5: immunolabelling by Alexa-Fluor 647 for alpha-smooth muscle actin (α-SMA) on myofibroblasts (red) and vascular walls in the liver  of mice chronically infected by Schistosoma mansoni using the indirect fluorescence technique
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