aPKC phosphorylation of HDAC6 results in increased deacetylation activity.

Here we show that PF-4708671 induces AMP-activated protein kinase (AMPK) phosphorylation and activation in immortalized mouse embryonic fibroblasts (MEF) independently of p70S6K1,

stably expressing HCA 1 -EGFP were transfected with specific arrestin siRNA or a non-specific control siRNA,72 hrs after transfection, cells were stimulated with 20 mM lactate for

Further, translocations involving induced DSBs on two different chromosomes are increased in frequency in either Ku or Lig4-XRCC4-deficient mouse embryonic stem (ES) cells,

The data are expressed as the specific activity in the mutant mouse tissues relative to WT controls 6 100 (% WT Idua Activity). p values above the brackets compare mice treated

When PTPRZ1-250- transfected HEK293T cells were co-transfected with HIF-2a in the presence of ELK1 siRNA, luciferase reporter activity decreased more than 75% as compared to

Because low levels of activated STAT3 were detected in MM1 cells [21] and luciferase activity was high in MM1 cells transfected with miR-155 promoter transcripts, we co-transfected

parvum infection increased luciferase activity in cells transfected with the luciferase constructs that encompassed the binding site for p65 at 2 1059 in the promoter region

When decitabine was used in combination with chidamide, significant increase in PRAME expression was observed in all 4 AML cell lines as compared with chidamide treatment alone