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Dissertation to obtain a Master Degree in Molecular Genetics and Biomedicine at Faculty of Sciences and Technology, Universidade Nova de Lisboa

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Academic year: 2019

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Figure 1.2 | Model of copper metabolism in humans. Ingested copper is absorbed from the gut, trans- trans-ported to liver bound to plasma proteins and distributed to cuproproteins
Figure 1.3 | Model of copper metabolism in hepatocytes. Copper crosses the plasma membrane through  either Ctr1 (Cu transporter 1) or DMT1 (Divalent Metal Transporter 1), and is shuttled to the trans Golgi  net-work by chaperone Hah1/Atox1, which delivers
Figure 1.4 | Iron distribution in the adult human body. A healthy individual absorbs daily 1-2mg of iron  from the diet, which compensates iron losses by cell desquamation in skin and the intestine
Figure 1.5 | Iron absorption in intestinal epithelium. Representation of iron uptake by enterocytes
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