Avaliação da susceptibilidade aos antimicrobianos e da diversidade genética de cepas de Streptococcus pyogenes isoladas no Rio de Janeiro

Texto

(1)012345627874 47458 0

(2) 214164 216 2 0 2

(3) 72 056 74 658708 ! 4

(4)

(5) 252 28 4 85862 28 8 28786. 8045 8"4 85#86. 838 28 78 6064 22 27874 86 81 2

(6) 252816 4 78 72345627874 41 28 74 486 74 $%&'$()())*+,'-(.&/&+ 26 8786 1 52 74 081425. 12 452 1234.

(7) 1 . . 3456789 5

(8) 8

(9) 595. 5545 5 6

(10) 8 7458 5 5

(11) 975 8 5. 8958 38

(12) 5 8

(13) 8 5 8. !"#$%&" 455 9 8 '589. ())*+,-./0 -1+*)*2,-3- -0

(14) 4+)0 3* 5). 3+-34-./0 67&"! *8 (9+0:(0;0<(- *. -+-)(,0;0<(- 51;(9-3-) 3- 62(=*+)(3-3*. >*3*+-; >;48(2*2)*? 9080 +*@4()(,0 1-+9(-;. 1-+- 0:,*2./0 30 ,A,4;0 3* *),+* *8. (9+0:(0;0<(-B. +(*2,-30+-C +0DEB +EB 955 9

(15) 5 7599. (,*+5(. FGHI.

(16) 1. 2345678 4

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

(18) 1. . . 4567895 5

(19) 9 8 6 55 695. 9

(20) 6 7 79

(21) 95. 9

(22) 5 575

(23) 76 65565

(24) 75 55 897 559 97955 65

(25)

(26) 5589 57. 58987

(27) 7 5. 5 .

(28) 1 34536789 7

(29) !"# $%&'&"%"( )*%'+%&,%-%%'&) %!&").&!!$%)%%- %%* %"/ ).&! !& %0%1&2&!%)&3"% .*4"#'(%5&6&& 7* 4"#/ 8!,%&( )%""&%,%&'3! "%#39"%#*: ;,%% &"%"-* 4"#"39"%#&%!<8=<<>?@AA 14<B&%)!"%A&%C&# &),D@AA!&+-&(4( E*F'* G"&"&'3 5-@AA!%-,%!,%%H%%! )A&<&!8I&;& H%,%!)8!J-!8'!0.!4(! GC!KL!%,%&+*4"#-; !&'3B'(!&.,%* M%"'().&F@AA!"L'& "&",%);%"%# &'G3*4" &%"8"(F%).&!,%& G3,%* ,%%3-!-.%&; -(*2%'" " %-* N.

(30) 1. . . 345789 8

(31) 8

(32)

(33) 99 8878 5 !"#$% &'

(34) 5

(35) ( ) *8+5

(36) ( ) *8

(37) 5 +

(38) )& ,-.$%#/0#$0.

(39) 1 234567 9

(40)

(41)

(42) !"#""$%"#"#"!"&'%"()*+(,- $%".$/01%"'0!!!.#23$#"!.$&'$!"!!$4'1$ .5"$'%'0$-$$"#!$67%$$5"!!.$%"$!%"8.9-$'%.#%1 #!"%!"1:&#";(!"&!$#"1<%."%.#1.-$.!" #"18!"$1.#"$8!"$1.0$%='#$%$4'$>/"1!$$=.#- $$"#!!.$.:%"$&.:%"$;?">0"!$$$'!"".0$&25"! $'$#%1!!"$.#"."$!@AA#%$!*+($"1!$%!$#25"! "".&)B@,"'$$#23$)B,-."%8"!"!CAADCA@C-##E25"!4'1$ $$.$"$#"18!"$-!.25"!"%"

(43) FF0125"!!0$!! &.#;G"1E!"$$$."8%#"$%!.#25"!$%#$$! $'$#%1!!"$.#"."$-%1""!"!!'$5"/&;($#%$$$.$ .!/"$#"18!"$"$'!$6!.25"!"$.:%"$!$$=.#- %1"$!%"725"!!$#"$-6!.25"!#".#.25".:8.)HI9, !"#.-%"!1'25"/&-6.0$&25"!"$!..$&.#"$! $$=.#-%"JHK;?$%"$

(44) FF"!.!"$%1"$4'.#."!&5" 0/01!"&.

(45) FF!0$!!&.#%1./1$!"$%$!&.25"!" LM(#""$$N#"%:$."#".E!$25"1""$&1 #%"%'1$!")JG+*,;O"!$$#%$"$'$#%80$6#7".-10"1"7#.- %.#1.+0.#"#.;G""$0!"$CAP!$$=.#6##1.-@QP6 #1.!#.@QP6"#.;?$.:%"$!$$=.##"18!"$"9RST# )@A,9RST)Q,"$&.:%"$"$0!"$"U

(46) FV)C,-

(47) FW)X,-

(48) FVY

(49) FW)Z, F

(50) [VY\Y

(51) FV)@,;O.""%"$$'%"$

(52) FF""$0!"$-%""$$ 4].$U

(53) FF^

(54) FF_

(55) FF^`

(56) FF``

(57)

(58) FFa^%$.QXP!$#%$ .1$!$;O=$."0"$$'%"$

(59) FF".#".!"$.$$$'!";(%!./1$! JG+*!"$%"$

(60) FF"%"$$801#".$4'$#%$$$.$#"18!"$ %$.%1!0$!!&.#.$-"4'!".$4'1##8$#.5" "1#".!6!$$.25"!'"'$#1".$;J"-"$0"'b$10! $1!!&.#.#%$%.#.$'$"%"

(61) FF;H<.25"" 10!".c"!#%$$$.$6"#.#"".:%"9RST-"4'.01E" '$"!#"18!"$1.#"$8!"$."."!.#23$%"*+(; defegheijklegmn9

(62)

(63)

(64) o$$=.#"$#"18!"$o!0$!!&.#o %"$

(65) FF;.

(66) 1 23456275 9

(67)

(68)

(69) !"#$%&%'()*+*%,) %&)%&-%./%))&/)0'%/%,*&/&&*%+1(*2*%*/ -%..3%&)/%))&4%&,2%50*%&%/0%(%*(0*678. /).%)*0&%&%%(%&2-.*0*(%/*&/(%&*0%/* .*%*(&*%+-.%.%*&.*+'&/2*%*/-%./%))& .&,*&/&,78.*%0).%/,-*+*(*.*&%0%'%*( %'%(%,)9::"#*%&%(*/)0.*,&*(%&!;9$*&/. %&!;$%&.%/)0<::=<:9<2*-((*..**%>*%&). %*&0*(%/2/0%&*%&)

(70) ??,*&/*0&)&%/%+%,7 @.&,%)%%/&%)%*%&-)0/*&/.*&%0%'%*( %'%(%,-/&',.**/%))%&0./74*(%/%*&*%& -'A/./0%&*%&)%*&.&,',/'(/%6*&/ ,.0,%&0%&%00%&.%'%, &&*%&!4BC$',**/%(%&0./7 B&+%*%&)&%%*&/0%&*&',@CD-**()0/78.

(71) ?? ,-/0%&/',1&%&.+*%*'(%&).

(72) ??&*&/. +*(*%&)&%/%+%,-*)0/',*&*(,%)0*%%&*&) .00*(EF'0%/(/G)%(/((.%!@H"I$7((%(*- %'()%*3&2(+)(3*%&2&%%((%&"*&/+*&0,%&7D%*&-* '+/*,(%&!<:J$2 (%&/*0,%&!9KJ$*&/,.0,%&!9KJ$78. .&,)0*(%/%*&-4L#M !9:$*&/4L#M%!K$*&/&,-

(73) ?N!<$2

(74) ?O!P$2

(75) ?NQ

(76) ?O!R$*&/?

(77) SNTUT

(78) ?N!9$78.%,G%.

(79) ??,*&/ ',-'+/2'.0)1&

(80) ??V2

(81) ??W2

(82) ??VX2

(83) ??XX*&/

(84) ??YV* &/)KPJ).*&*(,>/*0(78.&-

(85) ??',- )&/%&.%/,7M,@H"I*&*(,%*&/

(86) ??,%&Z[5\]^_\\Zàb]&(/.* 0*(%/%*&*%&&/-%/&%/%+%,2.)2..**%% -*&(*/.*/)&*)-(&7c-+2.%*&% %0%(*%,*0&*%&'(&%&&*0

(87) ??,7B%&-.,..%. &0'),.0,%&%*&*%&-%.4L#M.&,2-.%.+&.) 0*(%/*&/(%&*0%/%&.*0&)%&)%&',"#7 defghijkl9

(88)

(89)

(90) m0*(%/%*&m&%/%+%,m

(91) ?? ,%&7 .

(92) 1 23456896 9

(93) 365 64943264 64 65 !"#$%&'()*!'+,-.,"!'+/--!$.#/&. 264501%2#$'3/$%-'-#4& !&.'5!%"$6'(//-' 80+!&.!"2'7/"'8#2!%2!'+/&."/-'%&9':"!;!&.#/&' 3<=>?@ABCB 243+-#&#$%-'3%D/"%./")'5.%&9%"92'E&2.#.,.!' < FGHBIJ> 96K>>LGMM NOOP>JQ>JJCR NSOP>JQ>JJT>B>CJUGJ> BJBJQ>?VJCJ?VJJPMM W XYCPJJQ@>MM WZ[\]^_` <24 aA J T> B>CJ0>BCJ0 PBH WZ[\]^_`<aAJT>B>CJ Wb40aGUG cdSP>JQ>JJeBfgBFFhfgPiGj BG?kGUGJ>JBT>lQGUG 32FG> 3mWFQ ONnP>JQ>JJT>B>CJUGJ> BJoVJ@B@JQGo <p6PRq0r <p6s4PRq0rPG <3X0fBJR>@PYP.

(94) 12 345689.

(95) 8! " "

(96) " #58$ %" 8 " %" .

(97) &" ' ()*+,-

(98) ". $/0 "123 & " 4

(99) " 56,! " ++ 789,:"

(100) "- ;6,< "" " =6#6>,!- &" " 5569,?@" A'B " ' 539C8:BB - " ' D 59,:BB "- " ' EFG(HIJKLKM,NOPQROSTSTTUVWRXSYQZQV++ 558? "@-" ' 0 67,[" "" 65\5,0-"" 3,- 65+,9 ] "] ^838_Z`QaYbOQcWdeaPWfPSURWgQObScWàObWhPaObiQOaTWgQeZ . + + +.

(101) 11 234568932 45 6

(102) 94 !" #!$%&'()*+,+-#./! #".0123!.# " 2#4567 89#2:;<.!.#2".##:2".#+==.:#>! .#2!.4?57 @9#2:;<.!.#AB2".#+==C #02#./.D.!."E.!.!. #2!.4?57 F9!.DC !.#"0#!0DC2;<.!.9GH.C.##IC."/ 2J!KLM!" #!.#2".#+==NO+==P+==NQ4??7 R9!.DC !.#"0#!0DC2;<.!.9GH.C.##IC."/ 2J!KLM!" #!.2".+==QQ4?67 S9!.DC !.#"0#!0DC2;<.!.9GH.C.##IC."/ 2J!KLM!" #!.2".+==TN4?67. .

(103) 12 345679 67 375 6

(104)

(105) !"#$$!"$%&'( !"'()!"%*+,-. 6

(106)

(107) /0"$!"!$1234567898:&!;!"<"=! &(%'(">)?!$8@@&A!$)A!$! "%*+BC..

(108) 12 3456789. 8

(109) 7949 !! "!# !$!%& '(! $ )*+,-!. /0123452678519:7;4;9176. //<651454196:7;4;9176= > + )?-!-!@ $-!*@!-!/A BCDE7:FG76:9469396H21IJKLMNMO/ B/P7Q47;96DR264H4195ST96/ U !%! ,-!!!-@V!-/W X)!-!/Y Z%$ @+#!$) $!$ # -&!/[ \ 9]^_ 8`93BB a 5b _78b83 _ 5c 993B d 7_34e b93A f 83g4339W h g9

(110) ge439. i 7_j_7k

(111) g8b3 ]8]e89l76j8gb3./.

(112) 12. 356789

(113) 9 !"#$%&!'()*+(,-,--./!0&1!2341526&!3#42!3$1%#1$2!7#8!3&$!9144$&":!;<=>?@!32$2! 6#A1BC2$!D%2!526#12!6#!5&5&A!ED#!#4#!&FA#$7&D!#%!0#$162A!1C0#5"262A!;G+.H! IJKJLM!#"!24NO!<PP=@N! !BQC#$&!'()*+(,-,--./!3#$"#C5#!2&!014&!R1$%15D"#AO!542AA#! 9251441O!&$6#%!92514424#AO!02%S412!'()*+(,-,--G-*G*!;TUVVLWO!XYYX@N! LA!3$1%#1$2A!1C0&$%2Z[#A!A&F$#!'()*+(,-,--./\+],^*_*/!32$#5#%!"#$!A16&! 0#1"2A!3&$!`2A"#D$!;<=>P@!#!V&A#CF25:!;<==?@O!ED#!6#A5$#7#$2%!AD2!%&$0&4&B12O!&! 2A3#5"&!62A!5&4aC12A!#!AD2!71$D4QC512!32$2!52%DC6&CB&A!#!5&#4:&A!;G+.H!IJKJLMO! <PP=@N! '()*+(,-,--./\+],^*_*/!Ab&!5&5&A!c$2%!3&A1"7&AO!2$$2Cd26&A!#%!32$#A!&D! 526#12A!6#!2"e!fY!5e4D42A!&D!%21AN!L!0&$%2Zb&!#%!526#12!e!%#4:&$!71AD2418262!#%! %#1&!6#!5D4"D$2!4SED16&N!gAA#A!%15$&$B2C1A%&A!Ab&!2C2#$hF1&A!025D4"2"17&AO!52"242A#! C#B2"17&A!#!&i162A#!C#B2"17&AN!`&AAD#%!%#"2F&41A%&!0#$%#C"2"17&!62!B415&A#! A#C6&!&!j516&!4j5"15&!&!3$1C51324!3$&6D"&N!kb&!&$B2C1A%&A!CD"$151&C24%#C"#! #i1B#C"#A!ED#!C#5#AA1"2%!6#!%#1&!AD34#%#C"26&!5&%!A2CBD#!32$2!&!AD5#AA&!6&! 5D4"17&!l1C!71"$&m!;I MgTLM!#"!24NO!XYY<@N!! nj$12A!#A3e51#A!6#!'()*+(,-,--./!23$#A#C"2%!D%!52$F&16$2"&!C2!32$#6#! 5#4D42$O!&!52$F&16$2"&!oO!ED#!5&CA"1"D1!2!F2A#!62!542AA10152Zb&!A&$&4hB152!3$&3&A"2! 3&$!K2C5#01#46!#%!<PppN! !2C"SB#C&!3&41AA252$S615&!#A3#5S015&!6#!'q\+],^*_*/!e!D%! 3&4S%#$&!5&CA"1"DS6&!6#!$2%C&A#!#!Mr25#"14rsrB415&A2%1C2!CD%2!3$&3&$Zb&!6#!Xt<O! ED#!5&$$#A3&C6#!2&!B$D3&!L!6#!K2C5#01#46!;uVL9UKkJ!v!LKugVuwUTO!XYY=@N! LAA1%O!'q\+],^*_*/\e!"2%Fe%!5&C:#516&!5&%&!#A"$#3"&5&5&!6&!B$D3&!L!;gcL@O! 21C62!ED#!&D"$2A!#A3e51#A!3&AA2%!23$#A#C"2$!&!%#A%&!B$D3&!A&$&4hB15&! ;RLoIKLTO!XYYX@N!! T#%F$&A!62!%15$&F1&"2!6#!617#$A&A!AS"1&A!2C2"a%15&A!6#!610#$#C"#A! :&A3#6#1$&AO!24BD%2A!#A3e51#A!6#!#A"$#3"&5&5&A!Ab&!$#A3&CAj7#1A!3&$!D%2! 72$1#626#!6#!%2C10#A"2Z[#A!54SC152A!#!Ab&!5&CA16#$262A!1%3&$"2C"#A!2B#C"#A! 1C0#551&A&A!"2C"&!32$2!&!:&%#%!ED2C"&!32$2!&A!2C1%21A!;uVL9UKkJ!v! LKugVuwUTO!XYY=@N!.

(114) 12 346789.

(115) ! "# $ %& ' %& ()*+,*"- . /01-23324 56678! 0%& '' 9 # ' :; %& < $! =>?@ABCDEFG@HF@IJEKLMNOJB@ P' 'Q R $ 346789.

(116) : 4 ' # S ;4 %# '# $! T :; $ $ (,*+, !4 566U8! V %4 2W* # S ' %& $ ! X Q $4 R4 $ ' < $ 4 '4 # $ QR! X Q % ''4 ' Y < %#4 9 R$ :; '# :''Q $! V %&4 2W* '< ;$ R $%# 9 4 $ ! Z $ 9 'Q : %& $Y (,*+, !4 566U8! [\]\[^_àbcdae^fgd`hifjcjh`fe^^ k R : ("-*+/* !4 566l8! m!5!m!m 2 * "4 < 5l 4 ; ' R$Q4 R :; 9! * " ;.

(117) 12 34567859 4

(118) 64

(119) 54

(120) 75

(121) 75

(122) 434 75

(123) 7543

(124) 4

(125) 9 3

(126) 5 84

(127) 4

(128) 38437

(129)

(130) 453467 58

(131)

(132)

(133) 64647

(134) 4

(135)

(136) 87975

(137)

(138)

(139) 478

(140) 9

(141) 7

(142) 7!"87

(143) 4

(144) 8#

(145)

(146) 345675

(147) 87

(148) 396

(149) $755

(150)

(151) 6 4

(152) 4

(153) 5 3

(154) 49 5

(155) 475

(156) 4

(157) 6755 4 484

(158) 73 5

(159) 5

(160)

(161) 75 4

(162) 4

(163) 873675

(164) 8453467 58

(165)

(166) %&'

(167)

(168) 5

(169) 77

(170)

(171) 8 73

(172) 4

(173) 8(4)*7

(174) 453467

(175) 34484

(176) %$+,-.

(177) 4

(178)

(179) //01

(180) &2-3-4&

(181) //'

(182)

(183) 55

(184) -!77!8 5

(185) 637"8 5

(186)

(187) 73

(188) 5

(189) 4!77!8 5

(190) 637"8 5

(191) 453467 5

(192) %&$-5'

(193) 4

(194) 77

(195) 5643 84875

(196) 4

(197)

(198) 34567859 4

(199) 673

(200) 8 3

(201)

(202) 345675

(203) 84

(204) 55"

(205) 4 7

(206) 7

(207) 343 487

(208) 4

(209) 435 5

(210) 8 485

(211) 4

(212) 5

(213) 2

(214) 4

(215) 43 )*7

(216) 346488

(217) 4

(218) 78 5

(219) 8

(220) 733484

(221) 5 884

(222) 3 84

(223) 8(4)645

(224) 5

(225) %7.2&8

(226) 9

(227) ,:;8-++-

(228) 5<</'

(229) 5

(230) 5643 84875

(231) 45346775

(232) 454648

(233)

(234) 6 64

(235) 673 84

(236) 8

(237) 6 7"8454

(238) 5

(239) 8(4)645

(240) 5 5

(241) 673

(242) 45

(243) 456 4

(244) %&.:&=4>4

(245) 4

(246)

(247) 5<<'

(248) 5487

(249) 34567859 45

(250) 64 75

(251) ? 375

(252) 4

(253) 45 3 8

(254) 4

(255) 58374

(256) 7

(257) 7?4

(258) !7

(259) 4534677

(260) %&;2-'

(261) %@.&-.

(262) 4

(263)

(264) 5<<A'

(265) B

(266) 3 84

(267) 8C437

(268) 4

(269) 87 75

(270) 5643 84875

(271) (7

(272) 3 43# 7

(273) 7

(274) 787

(275) 75

(276) C 75

(277) 875

(278) 484

(279) 45 5

(280) 7!8 5

(281) 5*7

(282) 34784 5

(283) 77

(284) 5643 84875D

(285) &$-

(286) &$-;

(287) &$-E

(288) &$-8

(289) &$-:

(290) &$-F

(291) &$-=

(292) &$-+

(293) &$-,

(294)

(295) 7

(296) 5643 8487

(297) 4534677

(298)

(299) %&&'

(300) 4

(301)

(302) 4!77!8

(303) 7"8

(304) 453467

(305) 7

(306) %&,-7'

(307) %+:42E-&

(308) 4

(309)

(310) 5<<'

(311)

(312) &$-G

(313) 645 3

(314) 4

(315) 8*7

(316) 43

(317)

(318) )*7

(319) 4

(320) 5643 8487

(321)

(322)

(323) 673 84

(324) 4!77!8

(325) 5434

(326) 673

(327) HIJKLMNOPOQ

(328) -

(329) 637 7

(330) 875

(331) 7

(332) 7564437

(333) 87

(334) 34 484

(335) 8 5

(336) 3#45

(337) 75

(338) 475

(339) 875

(340) 77

(341) 8

(342) (37848

(343) 4

(344) 37848

(345) &$-G

(346)

(347) 4

(348) 47853 7

(349) 543

(350) 6 #

(351) 4

(352) 78 4343

(353) 63748 5

(354) 7 7 484

(355) 8 5

(356) 7

(357) 7564437

(358) 4

(359) (73 5

(360) 7 7 484

(361) 5

(362) 7

(363) 45

(364) 877 73 5

(365) 77

(366) 673

(367) 4!46 7

(368)

(369) 843 48

(370) :

(371) %:+R'

(372) -59

(373)

(374) 557

(375) S

(376) 43 )*7

(377) 4

(378) 85

(379) ( 7345

(380) 4

(381) 3 "8

(382) 4

(383) 453467775

(384) ?4

(385) 45*7

(386) 873 484

(387) 557 75

(388) S

(389) 5643(4

(390)

(391)

(392) 5

(393) 77

(394)

(395) ;

(396) 646 54

(397) 673 87

(398)

(399) &$-G

(400) 783

(401) 58( 484

(402) 6 3

(403)

(404) 6 748

(405) 75

(406) -E

(407) 8 5 4

(408) 8

(409) 743 784(34

(410)

(411) %.&,B&&-4

(412) 4

(413)

(414) 5<<51

(415) .>.:EB-7R:2B.G-

(416) 9

(417) ,B&&-.

(418) 5<<A1

(419) ;8

(420) 4

(421)

(422) 5<T'

(423)

(424).

(425) 12 345434689

(426)

(427) .

(428)

(429)

(430)

(431)

(432) !

(433)

(434)

(435)

(436)

(437) 4 " #$ "

(438) "

(439)

(440)

(441)

(442)

(443) %

(444)

(445) & '89 '

(446)

(447)

(448)

(449) #$()*

(450) 4'3++,-4.

(451)

(452)

(453) ' /0

(454)

(455) ""

(456)

(457)

(458) 89

(459)

(460) '

(461) .

(462) "

(463)

(464) 89

(465)

(466)

(467) 1

(468)

(469) (2345678*86/99/'5::+-4 345434;<

(470) %

(471)

(472) *

(473) =

(474) >.

(475) '

(476)

(477) "

(478)

(479) % '

(480) .

(481) #$ ' ? !

(482)

(483)

(484)

(485) (2345678*86/99/'5::+-' &

(486) '

(487) & 1& @

(488) ? "&

(489)

(490)

(491) #$! ' !

(492)

(493) '

(494)

(495) .

(496) ! #$1!

(497) '

(498)

(499)

(500)

(501)

(502)

(503) A

(504) '&

(505)

(506) B

(507) '? #$

(508) %

(509) "

(510)

(511)

(512)

(513)

(514)

(515)

(516)

(517)

(518) '

(519)

(520)

(521) #$

(522)

(523)

(524)

(525)

(526)

(527) ' & '.

(528)

(529) "

(530) 1!'

(531)

(532) #$! (54/C/.5'3++D-4 EFGFGHIJKLMKMLNJHOPQMQNLPJHH 345454381 1 /0'

(533)

(534)

(535)

(536) ' 1 & @'

(537)

(538)

(539)

(540) ? "&

(541)

(542) & '

(543) ' '

(544)

(545)

(546)

(547) &

(548)

(549)

(550)

(551) R !

(552) (2345678*86/99/'5::+-4.

(553) 12 3454545789.

(554) 89 89. 89 !" 89 !# 98"$ %& !889" 8!$'!(89)! 98

(555) *+ ! $ !8+,! ! !-!+ 9 "8. / 989 "8 90"! + 9 818! 998 % 28 8! (! 3 !4 * 9 "8 !$8 98 0!)9 !8 0!)9!$'!+ 1 85! !8%88 6 89(78. 8 4+599:;<./=>?7@

(556) >ABBA+599C*4 D 8+%8!9 81 8 E9 "87+! 98 89!!8 089 #!9 '!8 %898 9 ! %! -$! 8 ! 4F 345454G79 "87F 9 "87%89 "80!)9! 89+%8 88 !8 ! " !809%8 %80!$98H6 %8 082 ! 4A 8 983 898 8 8 ! $ !8 889. 88 90"! 8 89I 8 3 898098 8, 84= 8%82 #89!89 9 J3KL94D8+ 89 %8 18! 8 1'!8 9 !H6 %8% 84

(557) 8 88 !8 2% "% 9 89 "87!" 891899 $!M 9 !H6(8D* 1 !0 9 %8%82 8 1'!8 8%!,! 49 $!M

(558) D+ 9-5!%8E89. 89+68 8% 9#8 8 9 9!+ 18 $% $! +9 $!6N+! 98 8%89 $!6 %!3#89!,# 49H6 %8! 5 98 89 "87+9 $!6(8%!3 9%!8 O3 9%!8 *+8 8% #89!,# !!89 $!6 8 8 !0!! 8 898 !0 9 9! (P@=

(559) >A//@ 8 4+3CLC;8A>7

(560) QA 8 4+5939*4F A89 "888R !$8980!)9!$'! 2. !9) 1 8 8 !$8H6 % % 8 ! $ !8)I8 4@ 9%! 8 )9 #!#'!8 %!99$8!%9!!)!9808$! 4

(561) 81 59 8%8 9 "879 ! %E08$! +% ! !8%3 98! 8% ! 2%8. !!!8%9 !0 !4S 98 % +8-%8!0 H68$ 8+. # # %3 8!9 "0!98! 9 "87 # #! 9 !0 !(<./=>?7@

(562) >ABBA+599C*4 9!81 5 !89 8 6%% 8 8848 9!% !98 8)89!8898 98989 6. 9,!8 2. !9.

(563) 12 3356789 6 6 7

(564) 6 33653536 97597 96976 96

(565) 37 37 765937793 6356789. 6 6 7

(566) 6 653536 3 96

(567) 335678939 99! 96

(568) 3"356789# 9639"$%&'676

(569) 3!6 69 97 (3 6)*633567896+399. 59!97,-. 6776#39976! 9 6 36 96/33 35 6597 9370(123,463 !5667 865939 /89396 3 3 689+6 3 6 53 96

(570) 3!56 6/37 337673 6899 333763 33566 3/89599:3 66 6773566 3/896 3 63 )3539 69563 3773/8979 9 3 9973 9 1663;366 5!656<=!9 !9935 6963 )3/8956 6959 9379 6 3 67993%016976*636939959>3.! 6759977

(571) 6 563 3 3/?67 69

(572) 537966*69533 96

(573) 3 !966@AA8B,.63 !<C55 76*63695966@AA973376533/899 6 3 ! *6 65)99$,.;;63 !566D.3 66!37565'CC76*63759 66@AA 59979767976789 735973376565359759 E@FG@HIJ KLHJ MNI@OI@J ELFGHLPJ OFQJ RH@S@FGNLF 0>0 TUU59 UU697V5763767U96+U76U!36773596C'U5<U5W 9@AA56596 976*6369597 6 97<&C 69

(574) 5697 5966*695339 /89396 3 53 96

(575) 3.3765653597590>0 95373776*3756976797@AAX563537! 9 666756 959959!*678993663593537367639395653597 Y 375673776*3756667@AA378969 35379-6$3Z. 376565359759-6$3Z76 6 6 3533675335/89563539 3 76*3!3566 3 655[335673/8959797@AA .5673/8956976797@AA9656637763563 3 3/89 537 3 535653776*3786*3793 6 3/?673 689&\5966 @AA!6 6 3/893993 63 7895673537999 97979797 .3 735997697 6 975&C 69

(576) 56975376*35966!3 3

(577) 56756 7 3 53566 66666<]!3

(578) 59799 6^6 9!@AA_àbJ @AA_`cbJ@AAdàbJ@AAd`cbJ@AAacàbJ@AAac`cb6>66 39769 9797 @AA *359 3 7 3 5356 6 9 3 6<] +TUUeee59 U595U96+U7 6U377+!367735965CU55U5W .566 3/89599@AA6369 69 [33 37656 3 57 /89537397 37 367635353 689!*69 73 6)!.

(579) 12 34567895 7

(580) 77

(581) 7

(582)

(583) 59895

(584) 9

(585) 7

(586) 9 698 7

(587) 67

(588) 5399

(589) 49

(590) 7

(591) 98

(592) 9

(593) 788

(594) 77

(595)

(596) 6995 895

(597) 69

(598) 9 7 7

(599) 757

(600) 79767

(601) 57

(602) 957

(603)

(604)

(605) 59895

(606) 9

(607) 7

(608) 6 4

(609) 7

(610) 69

(611)

(612) !!

(613)

(614) 7 75 9

(615) 8 76

(616) 569756"9

(617) 49

(618) 7

(619) 877

(620) 6

(621) 676

(622) 6 59

(623) 9399"9

(624) 7

(625) 79

(626) 69

(627) 87

(628) 9567

(629) #567

(630) 78$

(631) 9756"9

(632) 98

(633) 5 7

(634)

(635) 9 46

(636) 6 59$

(637) 97"9

(638) 8 76769

(639) 57

(640) 6 4

(641) 6

(642)

(643) !!

(644) 95 9

(645) 79

(646) 6995 6$

(647) %7

(648) 9

(649) #87

(650) &7 57$

(651) 8

(652) 97 '57$

(653) 59 7

(654) 698$

(655) 6

(656)

(657) ()*(+)*+,)*-

(658) 9

(659) .$

(660) 5 7 756

(661) 8

(662) 7

(663) 6 4

(664) 9767

(665) 57

(666) %37

(667) 9

(668) 99

(669) 6

(670) /73

(671) 012334

(672) 9

(673) 7 $

(674) 566778

(675)

(676) 39#

(677) 8 78

(678) 7567

(679) 78 7

(680) 696769

(681) 9

(682) 9 4

(683) 8 94 7$

(684) 8 4 5767

(685) 9 7

(686) 758

(687) 95 7

(688) :5 7

(689) 95 9

(690) ;7

(691) 9 7

(692) <

(693)

(694) 976

(695) 4756

(696) 8 776

(697) 8

(698) 4

(699) 9 9

(700) #

(701) 74

(702) 69

(703) 959

(704) 69

(705) 9 '57

(706) 7 7

(707) 69

(708) 37

(709)

(710) 9 5;9

(711)

(712) 7569

(713) 7 9

(714) 67

(715) 696769$

(716) 53956

(717) 5

(718) =

(719) 37 9

(720) 69

(721) 4 '57

(722) 776

(723) 7

(724) 37$

(725) 87

(726) 788

(727) 74895 756

(728) 7

(729) 9'57

(730) 69

(731) 7 7

(732) 5 7

(733) 7

(734) 69397

(735) 6

(736) 969

(737) 0>#42#1?

(738) @

(739) <A?3&&3$

(740) 56678

(741)

(742) BCDEFGHGIJKLMNEKNEOGPMLMKNEQRONKNE 3 9

(743) 6

(744) 4

(745) #

(746)

(747) 7 =95

(748) 9S 79 4 79

(749) 49

(750) 64:98

(751) 487

(752) 796769

(753) 69

(754) 5399

(755) '57

(756) 95 956

(757) 898757

(758) 847$

(759) 9 9

(760) 9

(761) 96

(762) 87

(763) 3456

(764) T95 9

(765) 7

(766) 5399

(767) 74767

(768)

(769) 99

(770) 8758

(771) 955 78"9U

(772) 375 9$

(773) 8 9 V 6987$

(774) 9 9 7$

(775) 9 4 9$

(776) 97 7 57$

(777) 7 9987$

(778) 37 9

(779) 5975 9

(780) 9

(781) 5689

(782) 6

(783) 49

(784) =S

(785) 38

(786) 7 45

(787) 7

(788) 7

(789) 5399

(790) 698

(791) 97

(792) W

(793) 9X9 7

(794) 9 9 =7

(795) 5

(796) 4 47 7

(797) 8

(798) 399

(799) 948; 7

(800) 9

(801) 894 593 9

(802) 0AYZZ<Z9?#$

(803) 56668

(804) #

(805) 5399

(806) 74767

(807)

(808) 99

(809) 8758

(810) 9

(811) 7767

(812) 7

(813) 48

(814) 537

(815) 74

(816) 69

(817) 86769

(818) 9

(819) 8 7 6769

(820) 98

(821) 6

(822)

(823) 8456

(824) A8 79

(825) 8

(826) 9 9$

(827) 594857

(828) 9

(829) 8955 9

(830) 698

(831) 9$

(832)

(833) 49

(834) 69

(835) 97

(836) 7

(837) 48

(838) 6939

(839) 37 7

(840) 0AYZZ<Z9?#$

(841) 56668

(842)

(843) [7 9

(844) 6

(845) 969

(846) 8

(847) 6769$

(848) 6957

(849) 4\795 9$

(850) 695 9

(851) 9 7

(852) 679 9$

(853) 79 7

(854) 4

(855) 4 7

(856) 99

(857) 4 ]597

(858) 7467

(859) 4

(860) ^57$

(861) 8 7895

(862) 69

(863)

(864) 9 93$

(865) 8

(866) 4