Turning Up the Heat: Inflammasome Activation by Fungal Pathogens.

As shown in Table 1 and Figure 1, anticancer drugs effectively prevent yeast to hyphal form transition induced by 10% se- rum.. Among the four antimicrotubule anticancer

Nitric oxide production by human intestinal epithelial cells and competition for arginine as potential determinants of host defense against the lumen-dwelling pathogen

brasiliensis PAMPs that can induce inflammasome priming (pro-IL-1 b production), we pretreated the murine cells with the spleen tyrosine kinase (Syk) inhibitor piceatannol

Although new species of fungi are regularly identified as cause of disease in immunosupressed hosts, most of the reported op- portunistic fungal infections still remain candidi-

Since these two initial reports concerning the IFN γ R1 gene, as a cause of the unique susceptibility to atypical mycobacterial infections in childhood, several other mutations

capsulatum cell wall components with lectin-like activity seem to interact with the host cell surface, while host membrane lectin-like receptors can recognize a particular

This review will summarize current knowledge, including our own efforts, about pathogen, host and en- vironmental factors that influence, and contribute to the pathogenesis of

The importance of MyD88 in host defense in cryptococcal infection was demonstrated when MyD88-deficient mice exhibited de- creased survival and increased fungal burden in the