Antisense Oligonucleotides Modulating Activation of a Nonsense-Mediated RNA Decay Switch Exon in the ATM Gene
Texto
Imagem
Documentos relacionados
The mecha- nism of splice site selection in constitutive and alterna- tive splicing are closely connected, since components of the splicing machinery, essential for
We have proposed a hybrid architecture, where a central node has the next components (Figure 2): i) a master DFS instance which is responsible for managing the filesystem’s
As no significant differences in the cleavage of duplexes formed by D4676 and LD4676 and their respective modified ASOs were observed ( Fig 6C ), it was concluded that the
MPS I is caused by mutations of the IDUA gene, these including missense and nonsense, splice-site, and insertion or deletion mutations. The Han Chinese ethnic group is the most
Figure 7. Inhibitory effect of antisense TcCaNA2 oligonucleotides on T. cruzi cell invasion and proliferation. After washes with PBS and staining with May- Gru¨nwald Giemsa, the
Key words: Molecular biology, molecular imaging, PET, nucleosides, nucleotides, nucleic acids, oligonucleotides, antisense, aptamer, spiegelmer.. Author for correspondence
Key words: antisense oligonucleotide-mediated splicing redirection mutations, exon skipping, mismatch repair, mutation-targeted therapies, translational readthrough..
DNA fingerprinting of Fusarium solani isolates by using intron splice site primer EI1.. M: