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Quím. Nova vol.34 número5

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Figure 2 shows the aqueous solutions UV Spectra of (A) binary  mixture (15 mg L -1  of AZT and 7.5 mg L -1  of 3TC); (B) commercial  tablet, (C) AZT 15 mg L -1 ; (D) 3TC 7.5 mg L -1  and (E) placebo
Table 1. Validation of the irst (D 1 ) and second (D 2 ) derivative method
Table 4. Results for the analysis of tablets from ive different manufacturers, A, B, C, D and E (n = 8)
Figure 3. Dissolution proiles for AZT+3TC tablet from laboratory A, em- em-ploying HPLC, PLS, irst (D 1 ) and second (D 2)  derivative methods

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