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APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction.

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Fig 2. Pericyte loss and increased endothelial transcytosis in the aged cortex. (A) Reduction of PDGFRβ + pericytes (magenta) and laminin capillary coverage (green) is evident in the aged cortex when compared with the young cortex
Fig 3. Microglia/monocyte density is increased in regions with pericyte loss in the aged cortex
Fig 4. Astrocytic AQP4 is decreased in aged cortical astrocytes. (A) AQP4 immunoreactivity (blue) and protein levels (B) are significantly decreased in the aged cortex
Fig 5. Exercise improves behavior and neuroplasticity in aged mice. (A) Experimental strategy for voluntary running experiments (Sd = sedentary, Rn = Runner, Sac = sacrifice)
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