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Metabolic profiling provides a system understanding of hypothyroidism in rats and its application.

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Academic year: 2017

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Figure 1. The Body Weight (BW) profiles during the model and treatment periods. (box represents Sham group, triangle represents Sham + SND group, dot represents Hypo group, diamond represents Hypo + SND group, inverted triangle represents Hypo + T 4 group)
Table 3. The result of stability and repeatability of the proposed method.
Figure 4. Identification of a selected marker ( m/z 124.0082). (A) Extracted ion chromatogram (EIC) of m/z 124.0082 (t R = 0.69 min); (B) MS/MS spectrum of the ion in the urine; (C) MS/MS spectrum of a commercial standard
Table 4. Potential Biomarkers and their Metabolic Pathway.
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