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Lipoic acid, but not tempol, preserves vascular compliance and decreases medial calcification in a model of elastocalcinosis

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Academic year: 2019

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Figure 1. Effects of tempol or lipoic acid on vascular remodeling assessed in rabbits using in vivo radiofrequency-coupled  ultra-sound after 12 weeks of treatment
Figure 2. A, B and C, Systolic blood pressure, diastolic blood pressure and pulse pressure measured with direct catheterization in  anesthe-tized rabbits immediately before euthanasia.
Figure 4. Organ-bath vasoreactivity studies in rabbit aortic rings. Contractions to 0.1 mM noradrenaline (A), 0.12 M KCl (B) or 0.1 mM  L-NAME (C)
Figure 5. Upper panels, DHE fluorescence (red) in control and HCD-fed rabbits in the absence or presence of tempol or lipoic acid (LA)

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