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Inferring gene-phenotype associations via global protein complex network propagation.

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Academic year: 2017

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Figure 1 depicts the overall network structure used in RWPCN.
Table 2. Overall performance of BIOMART06, 09 and 06 + 09 phenotype-gene data. Phenotype-gene data Whole genomeevaluation Ab initio evaluation BIOMART06 253 226 BIOMART09 273 247 BIOMART06+09 285 253
Figure 3. KNN phenotype network on whole genome and ab initio evaluation. This figure studies the effect of the parameter k that decides the number of related phenotypes
Table 4 showed our prediction results for Diabetes Mellitus type 2. Out of the top 20 predicted disease genes, 8 genes were known to associate with the phenotype
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