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Exosomes isolation and characterization in serum is feasible in non-small cell lung cancer patients: critical analysis of evidence and potential role in clinical practice

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Academic year: 2019

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Figure 1: Schematic model of exosome origin and release.  Exosomes derived from the intraluminal vesicles (ILVs) of multivesicular  bodies (MVBs), formed through the reversed budding of the membrane of late endosomes
Figure 2: Role of exosomes in NSCLC.  Exosomes have a key role in : 1 horizontal transfer of mRNAs and miRNAs from cancer  cells to cells of microenvironment; 2 tumor progression, inducing cells motility; 3 angiogenesis; 4: metastatization; 5: immunosuppre
Figure 3: Summary of clinical case report.  The upper part of the figure shows the computerized tomography evolution

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