Anti-tumor necrosis factor drugs
Research Article TRAF1C5 but Not PTPRC Variants Are Potential
... cases, anti- tumor necrosis factor (anti-TNF) therapy has become a cornerstone of RA treatment strategy ...These drugs have revolutionized RA treatment and prognosis in the last ...
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Clinics vol.66 número7
... of anti-tumor necrosis factor/disease- modifying anti-rheumatic drugs and glucocorticoid use were also similar in both ...
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A Narrative Review on Anti-Tumor Necrosis Factor α Therapies in Inflammatory Bowel Disease During Pregnancy: Immunoglobulin Placental Translocation and its Impact
... Discussion: Anti-tumor necrosis factor α agents are efficient treatments for moderate-to-severe inflammatory bowel disease and may ensure remission during ...these drugs cross the ...
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Tumor Necrosis Factor, but Not Neutrophils, Alters the Metabolic Profile in Acute Experimental Arthritis.
... of tumor necrosis factor (TNF) in this process in an acute model of antigen- induced arthritis ...different drugs: Etanercept, an anti-TNF drug, DF2156A, a CXCR1/2 recep- tor ...
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Increased production of tumor necrosis factor- α
... nourished and control children included the distribution of SD for the three indices (weight/age, height/age, weight/height), as recommended by the WHO (22,23). From triceps skinfold thickness and mid-upper arm ...
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Rev. Bras. Reumatol. vol.57 número6
... A 44-year-old female had been followed-up with the diag- nosis of RA for approximately seven years. The patient had been using adalimumab 40 mg/2 weeks for three years. Fol- lowing adalimumab treatment, all complaints ...
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Imaging Tumor Necrosis with Ferumoxytol.
... early necrosis compared to T2 weighted or Gd-DTPA enhanced T1 weighted MRI ...of tumor necrosis with Gd-DTPA is based on lack of tumor perfusion and the typical hyper-intensity on T2 weighted ...
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Role of nuclear factor kappa B and reactive oxygen species in the tumor necrosis factor- α
... and tumor cells is still ...the tumor cells and the result- ing production of reactive oxygen species (ROS) ...nuclear factor kappa B (NFκB) could facili- tate the EMT in certain cell types (6-10) ...
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Erythropoietin reduces the expression of myostatin in mdx dystrophic mice
... TNF-a anti- body during early postnatal life clearly delayed and greatly reduced the breakdown of dystrophic muscle ...specific anti-TNF-a therapy has been ...
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Clinics vol.63 número3
... conceivable that PTX may exert some of its anti-inlammatory actions by affecting AP-1 activation and favoring CREB binding, thus inhibiting TNF-α gene transcription. Additional studies are necessary to elucidate ...
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Reactive oxygen species, apoptosis and cancer
... signals and is conducted through two major pathways: mito- chondrial (intrinsic) or death receptor pathway (extrinsic). Ex- trinsic pathway of apoptosis is triggered by interaction of death receptor and its ligand in ...
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Arq. Bras. Cardiol. vol.76 número5
... Characteristics of patients and control subjects are shown in the Table I. According to inclusion criteria, normal individuals were significantly younger than both groups of patients. Unstable angina accounted for the ...
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EARLY ACTIVATION OF SPLENIC MACROPHAGES BY TUMOR-NECROSIS-FACTOR-ALPHA IS IMPORTANT IN DETERMINING THE OUTCOME OF EXPERIMENTAL HISTOPLASMOSIS IN MICE
... into the spleen and induced the production of tumor necrosis factor alpha (TNF-a) locally.. The cytokine was.[r] ...
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Pentoxifylline decreases tumor necrosis factor and interleukin-1 during high tidal volume
... Pentoxifylline (PTX), a phosphodiester- ase inhibitor, has hemorheologic activity thought to be based on its ability to reduce blood viscosity, decreases serum levels of TNF-α, increases the filtrability of blood cells ...
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Necroptosis occurs in osteoblasts during tumor necrosis factor- a stimulation and caspase-8 inhibition
... Necroptosis is a regulated cell death mechanism. However, it is unknown whether necroptosis is involved in the death of tumor necrosis factor-a (TNF-a)-treated osteoblasts. Therefore, we conducted ...
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Biomarcadores inflamatórios e determinantes da síndrome metabólica em adultos jovens saudáveis
... 22 monoclonais, marcados no poço da microplaca, são dirigidos contra determinantes antigênicos da molécula de IL-6. Durante a incubação, a IL-6 presente na amostra reage frente aos anticorpos anti-IL-6. Após ...
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Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain.
... platelet-activating factor (PAF) is a potential ...of tumor necrosis factor a (TNFa) and interleukin-1b (IL-1b) expression in the injured DRG, crucial proinflammatory cytokines involved in ...
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Arq. Bras. Cardiol. vol.87 número1 en a05v87n1
... group. Factor VIII-c did not differ from that of the control group on admission, but it was signifi cantly higher at discharge, with no differences at three and six ...
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Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels.
... Competing Interests: Agneta Nordberg is PI for clinical trials sponsored by Torrey pines Therapeutics, GSK, Wyeth, and has been a consultant for AstraZeneca, served on the advisory board for Elan, Pfizer, GSK, Novartis, ...
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Avaliação da expressão de mediadores imunitários em amostras de cetáceos capturados acidentalmente em Portugal Continental
... características anti-inflamatórias, servindo como feedback negativo à produção da IL-1 e TNFα e aumentando a produção dos seus antagonistas (Schindler, et ...moléculas anti-inflamatórias (Tilg, Trehu, ...
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