Antiviral Agents
First discovery and stucture-activity relationship study of phenanthroquinolizidines as novel antiviral agents against tobacco mosaic virus (TMV).
... To control viral plant diseases, many approaches have been used, including chemicals, breeding, cross-protection and trans- genic plants. However, there are no control measures that can totally inhibit plant viruses ...
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Treatment of hepatitis C virus genotype 3 infection with direct-acting antiviral agents
... direct-acting antiviral agents (DAAs), NS3/4A protease inhibitors (telaprevir and boceprevir) became available for HCV genotype 1 infection and their association with PegIFN/RBV improved the sustained viro- ...
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Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents.
... As hypothesized, inhibiting SKI-1/S1P-mediated SREBP en- doproteolytic cleavage events using Spn4A.RRLL(s) resulted in a dose-dependent decrease in HCV infection. We demonstrated that HCV core expression and HCV RNA ...
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Systemic corticosteroids and early administration of antiviral agents for pneumonia with acute wheezing due to influenza A(H1N1)pdm09 in Japan.
... with antiviral agents and the median time from symptom onset to initiation of antiviral agents was 2 days (range, ...of antiviral agents and hospitalization ...
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Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents.
... for antiviral resistance and that the CLDN1-specific mAb OM-7D3-B3 used in this study appears to have a higher genetic barrier than the SR-BI-specific mAb ...
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Rev. bras. farmacogn. vol.22 número4
... and antiviral properties of several marine natural products obtained from seaweeds: the indole alkaloid caulerpin (CAV, 1) and three diterpenes: 6-hydroxydichotoma- 3,14-diene-1,17-dial (DA, 2), ...The ...
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Atividades farmacológicas dos flavonoides: um estudo de revisão
... ABSTRACT: The use of natural products as a raw material for drug synthesis has been widely reported over time. Flavonoids, undoubtedly, are an important group among natural products, which is gaining special interest due ...
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Transplante de córnea em ceratite por herpes simples.
... Reação de rejeição ocorreu em 14 pacientes (36,8%), sendo que em 11 destes no 1º ano pós-operatório. A avaliação atra- vés do teste exato de Fisher mostrou associação estatistica- mente significante entre rejeição e ...
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Avaliação da ativação do sistema imune de planta pelo receptor NIK (NSP- interacting kinase) e identificação de um novo parceiro de NSP (Nuclear Shuttle Protein) de geminivírus
... A proteína NIK apresenta um domínio cinase conservado, além de possuir repetições ricas em leucina (LRR-leucine-rich repeat). Foi demonstrado que a proteína NIK se autofosforila, e que esta fosforilação antecede sua ...
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Compostos químicos e aspectos botânicos, etnobotânicos e farmacológicos da Byrsonima verbascifolia Rich ex. A. Juss.
... antifungal, antiviral, antimicrobial, molluscicide, antimutagenic, mutagenic, teratogenic, immunomodulatory, toxic and cytotoxic activities of the extracts of this ...
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4. ZIKA VÍRUS: O ESTADO DA ARTE.
... um antiviral e vacina contra o vírus são essenciais para compreender a dinâmica viral e estabelecer medidas de controle e prevenção da doença, consequentemente evitando suas possíveis ...
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Can antiviral drugs contain pandemic influenza transmission?
... use antiviral drugs to mitigate ...few antiviral doses. In contrast, persistent use of antiviral drugs when the reproduction number remains above 1 use very many doses and are unlikely to reduce the ...
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Broad-spectrum antiviral peptides against respiratory viruses
... Influenza viruses (IV) are major human pathogens responsible for respiratory diseases affecting millions of people worldwide and characterized by high morbidity and mortality. Infections by influenza can be controlled by ...
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Atividade antiviral de compostos naturais no ciclo replicativo do HCV
... A análise da atividade dos compostos no ciclo replicativo viral demonstrou que um composto natural pode agir em mais de uma etapa do ciclo realizada pelo vírus durante [r] ...
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Dynamic coordination among heterogeneous agents
... by agents in the decentralized equilibrium in ...the agents towards the best “fundamentals” (1 when θ is high, 0 when θ is low) but the planner actually cares less about fundamentals than the ...If ...
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SOFTWARE AGENTS IN NETWORK MANAGEMENT
... Traditional agents do not filter information, which results in growing network traffic and growing difficulty to process information in a centralised way (Figure ...
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Propagação in vitro de Hypericum cordatum (Vell.) N. Robson (Clusiaceae) e análise fitoquímica de seus compostos secundários.
... são antiviral e redutora do estresse oxidativo para a primeira, vasoprotetor capilar, para a segunda, e antioxidante para ambas (Dias, 2005; Cecchini et ...
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Triagem fitoquímica e avaliação da atividade antibacteriana de extratos das flores de Sambucus nigra L. (Caprifoliaceae).
... Sambucus nigra L. é uma planta arbustiva de origem europeia cultivada no sul do Brasil, e que possui propriedades semelhantes à espécie Sambucus australis (Cham. et Schlecht.). Há registro de seu uso na Idade da Pedra, ...
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A crystal ball made of agents
... HIS article introduces the application of the agents technology in the field of prediction. Mathematical models are useful to foresee how dynamic systems evolve. A social environment evolves as a dynamic system, ...
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THE AGENTS OF EDUCATION MARKET
... economic agents that are divided into two large categories: buyers and sellers”; let’s also notice that on the same market and within the same action (selling-buying) an agent can only play a sole part, either ...
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