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Basal-like breast cancer

LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition.

LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition.

... that basal-like breast cancer cells with overexpression of LSD1 may be sensitive to PARP inhib- itor via suppression of ...of basal-like breast cancer cells to PARP ...

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Identification of Personalized Chemoresistance Genes in Subtypes of Basal-Like Breast Cancer Based on Functional Differences Using Pathway Analysis.

Identification of Personalized Chemoresistance Genes in Subtypes of Basal-Like Breast Cancer Based on Functional Differences Using Pathway Analysis.

... Breast cancer is a highly heterogeneous disease that is clinically classified into several sub- ...subtypes, basal-like breast cancer largely overlaps with triple-negative ...

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Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients' Outcome in Basal-Like Breast Cancer.

Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients' Outcome in Basal-Like Breast Cancer.

... in breast cancer. Since breast cancer comprises heterogeneous intrinsic subtypes with distinct clinical outcomes we investigated the pivotal role of NDRG2 in basal-type breast ...

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A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response.

A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response.

... its critical role in proliferation, it is not surprising that aberrant or deregulated MYC expression participates in the malignant transformation of normal cells into cancer cells. Numerous high- throughput ...

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The differences in ultrasound and clinicopathological features between basal-like and normal-like subtypes of triple negative breast cancer.

The differences in ultrasound and clinicopathological features between basal-like and normal-like subtypes of triple negative breast cancer.

... of breast cancer and that is associated with relatively high rates of recurrence, distant metastases and low overall survival rates ...and basal-like subtype are usually thought to be ...

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Morphological Aspects and Immunophenotypic Profiles of Mammary Carcinomas in Benign-Mixed Tumors of Female Dogs

Morphological Aspects and Immunophenotypic Profiles of Mammary Carcinomas in Benign-Mixed Tumors of Female Dogs

... for breast cancer is a valuable tool for assessing prognosis and investigating similarities between the canine and human tumor ...human breast carcinomas were identified, based on gene expression ...

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Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells.

Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells.

... human breast epithelial cell organoids grown at 21% and 1% oxygen illustrated by the marker of breast epithelial differentiation and polarization laminin ...primary breast epithelial cells after 12 ...

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Clinics  vol.66 número6

Clinics vol.66 número6

... been obtained from such studies. Dufflot et al. 34 investi- gated the associations of polymorphisms in the genes XRCC1 , XPD, XRCC3, and RAD5 with tumor characteristics in 94 breast cancer patients. While ...

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RAD51B in Familial Breast Cancer.

RAD51B in Familial Breast Cancer.

... with breast cancer risk, two-sided P-values were calculated using Pearson’s chi-squared test or, if the expected number of cell count was less than five, Fisher’s exact ...all breast cancer ...

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Rev. Hosp. Clin.  vol.58 número2

Rev. Hosp. Clin. vol.58 número2

... to cancer recurrence, some of them (38%) would accept such therapy to control menopause symptoms, and late effects like ...of breast cancer treatment would influ- ence the acceptance of ...

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Depression and Anxiety Disorders among Hospitalized Women with Breast Cancer.

Depression and Anxiety Disorders among Hospitalized Women with Breast Cancer.

... hospitalized breast cancer patients need to be considered, including one or more diagnostic barriers at the individual, provider or institutional ...among cancer patients in Scotland ranged from ...

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Rev. LatinoAm. Enfermagem  vol.22 número3

Rev. LatinoAm. Enfermagem vol.22 número3

... Some participants felt that the sexual problems of the partner, for example erectile dysfunction caused by health problems, such as hypertension, or aging, were more relevant than the cancer. In the focus groups ...

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TOX3 mutations in breast cancer.

TOX3 mutations in breast cancer.

... in breast cancers and recently implicated in the risk of developing breast ...in breast cancer ...in breast cancers. We screened TOX3 for mutations in 133 breast tumours and ...

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Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

... Against Cancer; the Spanish Biomedical Research Centre Networks for Epidemiology and Public Health, and Rare Diseases; and the ‘‘Ramo´n y Cajal’’ Young Investigator Program), the Spanish National Society of ...

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Formal modeling and analysis of ER-α associated Biological Regulatory Network in breast cancer

Formal modeling and analysis of ER-α associated Biological Regulatory Network in breast cancer

... Previous studies suggested ER-α as an important therapeutic target for the management of BC pathogenesis (Ariazi et al., 2006; García-Becerra et al., 2012; Giacinti et al., 2006; Hanstein et al., 2004; Kang et al., ...

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Cytogenetic evaluation of 20 primary breast carcinomas

Cytogenetic evaluation of 20 primary breast carcinomas

... Breast cancer is the most common neoplasm and the leading cause of cancer related deaths among women in most countries (PARKIN et al. The natural history of breast cancer va[r] ...

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Association of MMP8 gene variation with breast cancer prognosis

Association of MMP8 gene variation with breast cancer prognosis

... Breast Cancer Res 2008, 10(Suppl 2):P80 (doi: ...Background Breast cancer patients commonly receive a combination of different therapies; however, our understanding of how such combined ...

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Barriers to early detection of breast cancer among women in a Caribbean population

Barriers to early detection of breast cancer among women in a Caribbean population

... of breast cancer, as well as current breast cancer screening behaviors and attitudes regarding the disease, among women aged 20 and older on the Caribbean island of ...of breast ...

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Long non-coding RNAs as potential therapeutic targets in human breast cancer

Long non-coding RNAs as potential therapeutic targets in human breast cancer

... Breast cancer is the most frequently diagnosed cancer and the second-leading cause of cancer death in women ...situ breast carcinoma (no evidence of invasion) was diagnosed in about ...

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Rev. Assoc. Med. Bras.  vol.59 número3

Rev. Assoc. Med. Bras. vol.59 número3

... without breast cancer was very interest- ...postmenopausal breast cancer survivors (BCS) than in postmenopausal women without breast ...

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